Dosage instructions
Dosage instructions1
Gina is a vaginal tablet. Each vaginal tablet comes preloaded in a single-use applicator. Every Gina pack contains 24 preloaded applicators. Treatment can be started on any convenient day.
INITIAL DOSE 1 vaginal tablet daily for 2 weeks, then follow maintenance dose.
MAINTENANCE DOSE 1 vaginal tablet twice a week, leaving 3 or 4 days between each dose.
Dosing regimen
| Mon | Tue | Wed | Thur | Fri | Sat | Sun | ||
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| Initial | Week 1One vaginal tablet per day |  |
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| Week 2One vaginal tablet per day | |
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| Maintenance | Week 3 and thereafterOne vaginal tablet twice per week (3-4 days apart) e.g. every Tuesday and Friday as illustrated | |
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Example day-of-week phasing
You can tell patients that there is a table in the leaflet that they can use as a reminder.
If they miss a dose, they can use one as soon as is convenient, but they should not use more than 1 vaginal tablet in 1 day. The next vaginal tablet can be used as planned.
Initiation and continuation of treatment should be at the lowest effective dose for the shortest duration.
You should discuss this with your patients when they purchase Gina.
However, patients should be advised that VA is chronic and progressive and symptoms are likely to return if treatment is stopped. Women can continue to use Gina as long as they wish to, unless they are no longer suitable, which may be for years if appropriate. You should check their continued suitability every 3 months when they return for their next pack.5
Use after a treatment break
Women who have had a treatment break from either using a previous local oestrogen or whilst using Gina will follow a dosage according to the severity of their symptoms. If bothersome symptoms have returned, advise them to start with the initial dose, otherwise follow the maintenance dose.5