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Chloramphenicol: side effects and contraindications
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Chloramphenicol: side effects and contraindications
There may be mild and transient stinging or burning in the eye on application and blurring of vision.
Chloramphenicol eye drops or eye ointment should not be used in patients who have a history of hypersensitivity to chloramphenicol or who have experienced myelosuppression during previous exposure to chloramphenicol, or those with a family history of blood dyscrasias.
The products are not recommended for pregnant or breastfeeding women.
Prolonged or frequent intermittent topical application of chloramphenicol should be avoided as it may increase the likelihood of sensitisation and emergence of resistant organisms.
Contact lenses should not be worn during the course of treatment, and soft contact lenses should not be replaced for 24 hours after completing treatment.
In the pharmacy, chloramphenicol eye drops should be stored in a refrigerator at 2-8C. Once opened, the drops should be discarded after five days. Storage for chloramphenicol eye ointment is at room temperature. Although the shelf-life once opened is 28 days, patients should be advised to discard the tube at the end of the five day course.
Chloramphenicol: side effects and contraindications
