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Renal therapeutics: part three

CKD criteria

Causes of CKD

Risk factors

Preventing or delaying progression

Pharmacological management

Other considerations

module menu icon Causes of CKD

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module menu icon Causes of CKD

Anyone can develop CKD and there are many causes. The following list is not exhaustive, but outlines the main causes:

  • Conditions associated with intrinsic kidney disease (those that affect the kidney’s tissues), such as hypertension, type 1 and type 2 diabetes mellitus, hypercholesterolemia
  • Kidney infections
  • Glomerulonephritis (inflammation of the glomeruli of the kidneys)
  • Medicines that are impactful on the kidneys, such as lithium, calcineurin inhibitors (e.g. ciclosporin or tacrolimus), aminoglycosides, mesalazine
  • Conditions associated with obstructive kidney disease
  • Multisystem diseases that may involve the kidney, e.g. systemic lupus erythematosus (SLE)
  • Hereditary history of kidney disease.

    • Renal therapeutics: part three

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