Stop smoking aids Varenicline, bupropion or NRT should be prescribed or provided before the person stops smoking. A quit date should be agreed within the first two weeks of treatment with bupropion, and the first one to two weeks of taking varenicline. The smoker should be reassessed “shortly before the prescription ends”. Those using NRT should also agree a quit date.

Varenicline (Champix)

Many patients find varenicline can reduce the pleasurable effects of smoking due to the blocking action it has on the nicotine receptors, while taking the edge off cravings. Common side effects experienced (approximately one in 10 patients) include nausea, headaches, insomnia and abnormal dreams. These may resolve over time but, if not, a reduced dose may be required.

Treatment should last for 12 weeks (extended for a further 12 weeks or the tapered dose depending on results). One tablet should be taken twice daily following a one-week titration.

Bupropion

Bupropion is indicated as an aid to smoking cessation in combination with motivational support in nicotine-dependent patients. Dosage is 150mg daily for six days, then 150mg twice daily with a minimum of eight hours between doses for a period of seven to nine weeks. Treatment should be started one to two weeks before the target stop date and discontinued if abstinence is not achieved at seven weeks.