Depression is extremely common, with one in 10 men and one in four women developing clinical depression during their lifetime. The World Health Organization lists depression as the second greatest cause of disability in the world. Depression can affect physical health, with sufferers often experiencing greater complications from pre-existing chronic health conditions, as well as having an increased risk of osteoporosis and heart disease.

There is undoubtedly a huge unmet need to support patients with this disorder. Depression can take many forms, from sadness, grief and disappointment to self-criticism and guilt.

However, the term 'depression' is often overused in daily life. A clinical diagnosis can only be made by identifying a cluster of symptoms listed in the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders €“ fifth edition). There are no blood tests or scans involved in the diagnosis. Depression varies in severity, and is classed as mild, moderate or severe.

In order to receive a diagnosis of a major depressive disorder, an individual must exhibit at least five symptoms that have been present for at least two weeks €“ but what does this mean in reality? Reflect on what patients experience during a depressive episode.

Individuals often find it difficult to enjoy anything and may alienate themselves from their loved ones, which heightens their loneliness. In addition, they can feel worthless and that life is not worth living. These thoughts can be so severe that people will often contemplate suicide and, sadly, some do take their own lives.